I have set up Yukon, Nitro and US GEAR Put them in Dana 60 , 14b, toyota 9, GM 12 bolt, Dana 35, dana 20, Chrysler AAM 11.5. and a couple others im sure. Overall most of the main stream brands are going to do fine with the proper set up. That being said a good set of bearings is worth more than the ring and pinion i think. Almost all gear failures can be traced to improper spacing. This can be from improper set up, bearing wear, or case deflection. I always try to set the gears based upon what weakness the axle or carrier may have and how its going to be used. The cryo treatment has value but it really is only going to be for that small percentage of people that really put a beating on gears beyond their design limits. Like Ultra 4 or hotshot carriers.. Plenty of diesels out there with 300k on the ticker and never had a rear end change.